Good Sam Club Open Roads Forum: Search
Open Roads Forum Already a member? Login here.   If not, Register Today!  |  Help

Newest  |  Active  |  Popular  |  RVing FAQ Forum Rules  |  Forum Posting Help and Support  |  Contact  



Open Roads Forum  >  Search the Forums

 > Your search for posts made by 'BCSnob' found 314 matches.

Sort by:    Search within results:
Page of 16  
Prev  |  Next
  Subject Author Date Posted Forum
Some people have no respect for others

We have a 1/4 long farm lane and for some reason done people seem to think it’s okay for them to do what they want because they cannot see our house. Today (early afternoon) someone pulled into our drive to use a big tree 1’ off our drive to relieve themselves of number 2. I guess our drive was acceptable where the gas station 1/4 mile up the road wasn’t close enough. Now we have a pile with paper 1’ off our drive near the mailbox. I’ll bet they would scream if someone took a dump near their mailbox. If I am expected to pick up after my dogs they should pick up after themselves.
BCSnob 09/05/20 02:47pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

Population-Based Estimates of Chronic Conditions Affecting Risk for Complications from Coronavirus Disease, United States Emerging Infectious Diseases We estimated that 45.4% of US adults are at increased risk for complications from coronavirus disease because of cardiovascular disease, diabetes, respiratory disease, hypertension, or cancer. Rates increased by age, from 19.8% for persons 18–29 years of age to 80.7% for persons >80 years of age, and varied by state, race/ethnicity, health insurance status, and employment. This is from table 1 in this study where the authors have estimated the percentage of the population by age with at least one underlying health condition that increases the risk for severe Covid-19 infections. Age, y % with at least 1 comorbidity 18–29 19.8 30–39 26.8 40–49 38.1 50–59 55.1 60–69 68.0 70–79 79.5 >80 80.7
BCSnob 09/04/20 10:09am Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

Minks infected by humans on mink farms. Then humans were infected by minks on these farms. Mink could be an animal reservoir for SARS-CoV-2 infections. It would be very bad if agricultural animals were reservoirs for this or other viruses that are readily communicable amongst those farm animals and to humans. Jumping back and forth: anthropozoonotic and zoonotic transmission of SARS-CoV-2 on mink farms doi: https://doi.org/10.1101/2020.09.01.277152 Experimental infections in dogs (10), cats (10, 11), ferrets (10, 12), hamsters (13, 14), rhesus macaques (15), tree shrew (16), cynomolgus macaques (17), grivets (18), common marmosets (19), rabbits (20), and fruit bats (21) have shown that these species are susceptible to SARS-CoV-2, and experimentally infected cats, tree shrews, hamsters and ferrets could transmit the virus. In contrast, experimental infection of pigs and several poultry species with SARS-CoV-2 proved to be unsuccessful (10, 21, 22). Since our observation, SARS-CoV-2 infections 364 have also been described in mink farms in Denmark, Spain and the USA (57–59), and mink farming is common in other regions of the world as well, also in China where around 26 million mink pelts are produced on a yearly basis (60). The population size and the structure of mink farms is such that it is conceivable that SARS-CoV-2 – once introduced – could continue to circulate. Therefore, continued monitoring and cooperation between human and animal health services is crucial to prevent the animals serving as a reservoir for continued infection in humans.
BCSnob 09/02/20 12:48pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

The infection rate in children of healthcare workers in the UK appears to be the same as in adults based upon the presence of antibodies. This suggests that children are no less susceptible to being infected. The study did find that 50% of the children with Covid-19 antibody titers reported have no symptoms suggesting they are less impacted by this virus. I have read that the amount of ACE2 receptor is correlated with age (source). Seroprevalence of SARS-CoV-2 antibodies in children - A prospective multicentre cohort study. doi: https://doi.org/10.1101/2020.08.31.20183095 This observational study is one of the largest UK studies of paediatric SARS-CoV-2 antibody seroprevalence, and the only study to recruit from all regions of the UK. Following the first pandemic wave in the UK, 68/992 (6.9%) children of healthcare workers had evidence of prior infection with SARS-CoV-2. Whilst this is likely to be higher than the general population it is surprisingly similar to the seroprevalence reported by the ONS study of adults from England and Wales (6.2%) (10), and similar to international estimates (11-13). As expected there was marked geographical variation, with London reporting the highest infection rates (11.6%) and Belfast the lowest (0.9%) p<0.0001. These regional variations are consistent with published adult estimates of seroprevalence from the same time period (10). In this study there was a near equal number of children under 10 years of age 32/68 (47%) and children over 10 years of age 36/68 (53%) developing antibodies consistent with previous SARS-CoV-2 infection. Age, as a categorical or continuous variable, was not a statistically significant factor in predicting the presence of antibodies, or the overall titres in children irrespective of the assay used (Figure 2). This is in contrast to several studies that have reported a lower seroprevalence in young children (under 10 years of age) and in elderly adults (over 65 years of age) following the first wave of the pandemic (11-13). This has led some authors to suggest that children are less susceptible to SARS-CoV-2 infection (27-30). The studies on which these assumptions are based have typically reported a binary antibody outcome (positive or negative) rather than absolute titres (11-13). It is possible that the lower seroprevalence reported thus far in younger children merely reflects the effect of social distancing measures on this group. This may go some way to explain why the over 65s also demonstrated lower seroprevalence in the same studies (27-30). In our cohort, children were more likely to be exposed to SARS-CoV-2 in the home due to fact that their parent(s) worked in healthcare. The findings from this study may therefore provide a greater insight into how younger children react when exposed to SARS-CoV-2. Further research is required to understand if younger children are really less susceptible to SARS-CoV-2.
BCSnob 09/02/20 10:47am Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

I’ve been meaning to post this. You (as I am) can daily check the latest preprints of Covid-19 research articles here: COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv
BCSnob 09/01/20 02:48pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

https://www.google.com/amp/s/amp.cnn.com/cnn/2020/08/19/us/sturgis-south-dakota-rally-coronavirus-trnd/index.html
BCSnob 08/30/20 12:54pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

From Minnesota MDH COVID-19 briefing Cluster outbreaks/Sturgis: Infections related to the Sturgis Motorcycle Rally in South Dakota that took place earlier this month are continuing to rise. Infections related to the event now stand at 46 confirmed cases with two individuals being hospitalized, one of which is in intensive care, Ehresmann said. MDH is also beginning to see secondary transmission from the Sturgis cases. While those cases are not included in the total of 46, they are a concern, Ehresmann said. She also said that they are expecting to see more secondary transmission from these cases as the days continue. Some of the secondary transmission from Sturgis cases came from a wedding, according to Ehresmann. MDH is concerned about an increase in cluster cases involving weddings, parties and other gatherings that are not following social distancing or masking recommendations.
BCSnob 08/29/20 09:37am Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

Here is a report of Nevada man that had a second covid infection with a different variant than the first time. This one put him in the hospital. https://arstechnica.com/science/2020/08/another-covid-19-reinfection-this-time-second-infection-was-more-severe/You forgot to mention that unlike the other reported cases they don’t know if the first infection in the man in Reno lead to seroconversion. Where with the vaccines they will be measuring seroconversion for multiple locations on the virus. As it was noted previously not all antibodies are “neutralizing” (evidence suggests the antibodies against spike subunit 1 where the RBD is located) and not all antibody tests measure the the same antibodies. Without knowing which antibodies were measured for the others who have been re-infected there is no way to know if the first infected yielded neutralizing antibodies.
BCSnob 08/29/20 06:12am Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

Assuming the covid-19 vaccines are as effective and have the same DOI as the measles vaccine; once you’ve been vaccinated you no longer need to worry for yourself when herd immunity is reached. Just don’t be an antivaxxer. Even if there was 100% vaccination rate for the seasonal flu; herd immunity will not be obtained.
BCSnob 08/28/20 06:35pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

A newly published study with information on the viral loads in children with Covid-19 Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Responses Journal of Pediatrics Here is one key takeaway: Nasopharyngeal viral load was highest in children in the first 2 days of symptoms, significantly higher than hospitalized adults with severe disease (P = .002). Age did not impact viral load.... Here is another key takeaway: This study reveals that children may be a potential source of contagion in the SARS-CoV-2 pandemic in spite of milder disease or lack of symptoms....
BCSnob 08/28/20 02:53pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

Despite also falling under the cold chain transport, we seem to have enough influenza vaccine every year.
BCSnob 08/28/20 02:35pm Around the Campfire
RE: Coronavirus

Add rabbits to the short list of animals that can become infected with SARS-CoV-2. This study did not investigate if rabbits inoculated with the virus can pass the virus onto humans. Susceptibility of rabbits to SARS-CoV-2 Abstract Transmission of severe acute respiratory coronavirus-2 (SARS-CoV-2) between livestock and humans is a potential public health concern. We demonstrate the susceptibility of rabbits to SARS-CoV-2, which excrete infectious virus from the nose and throat upon experimental inoculation. Therefore, investigations on the presence of SARS-CoV-2 in farmed rabbits should be considered. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a pandemic only months after its discovery in December 2019 (1). Slowing down its spread requires a full understanding of transmission routes, including those from humans to animals and vice versa. In experimental settings, non-human primates, ferrets, cats, dogs and hamsters have been found to be susceptible to SARS-CoV-2 infection (2-4). Moreover, ferrets, cats and hamsters were able to transmit the virus via the air (2, 4, 5). In domestic settings, both dogs and cats have been found to carry the virus, displaying very mild to more severe symptoms, respectively (5). Recently, SARS-CoV-2 has been isolated from mink at multiple Dutch farms. Workers at those farms carried viruses that were highly similar to the viruses detected in mink and phylogenetic analyses supported transmission from mink to workers (6). Thus, measures to control the spread of SARS38 CoV-2 should also include preventing spill over into potential reservoirs, especially since infectious agents can spread rapidly in livestock due to the high densities at which some animals are kept. Given the fact that rabbits are commonly farmed worldwide, we investigated the susceptibility of rabbits to SARS-CoV-2.
BCSnob 08/28/20 07:13am RV Pet Stop
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

Most of our products are shipped cold; if we were loosing 25% it would be a major topic in meetings. Thus us especially true since many of our popular products are priced at $1000 a unit.
BCSnob 08/28/20 04:39am Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

From the linked article on the mRNA vaccines Executives from Moderna and Pfizer on Wednesday separately told the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practice on Wednesday that mRNA-1273, which is Moderna’s coronavirus vaccine candidate, requires a storage temperature of negative 4 degrees Fahrenheit. BioNTech and Pfizer’s candidates, BN1162b2 and BNT162b2, need to be stored in negative 94 degrees Fahrenheit.. Why won’t dry ice work?
BCSnob 08/27/20 08:22pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

You’re right; I miss read the chart. When desired products require very cold shipping someone figures out how to do it. Take a look at bull or horse semen. This might make you feel better about the distribution of the vaccines. Distribution: Before the countermeasures are approved or authorized, the program will build the necessary plans and infrastructure for distribution. HHS plans for a tiered approach to vaccine distribution, which will build on allocation methodology developed as part of pandemic flu planning and be adjusted based on experience during the first wave of the COVID-19 response, data on the virus and its impact on populations and the performance of each vaccine, and the needs of the essential workforce. OWS will expand domestic manufacturing and supplies of specialized materials and resources, such as glass vials, that can be necessary for distribution. DoD’s involvement will enable faster distribution and administration than would have otherwise been possible. Select actions to support OWS distribution efforts include: May 12: DoD and HHS announced a $138 million contract with ApiJect for more than 100 million prefilled syringes for distribution across the United States by year-end 2020, as well as the development of manufacturing capacity for the ultimate production goal of over 500 million prefilled syringes in 2021. June 9: HHS and DoD announced a joint effort to increase domestic manufacturing capacity for vials that may be needed for vaccines and treatments: $204 million to Corning to expand the domestic manufacturing capacity to produce an additional 164 million Valor Glass vials each year if needed. $143 million to SiO2 Materials Science to ramp up capacity to produce the company’s glass-coated plastic container, which can be used for drugs and vaccines. Fact Sheet: Explaining Operation Warp Speed Shipping at the storage temperature is not the issue; shipping and distribution of 300 million doses around the entire country is the issue.
BCSnob 08/27/20 07:39pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

Likely not much of a market for -80C. https://pharmaceuticalcommerce.com/special-report/advancing-biopharma-cold-chain/Based upon your link it’s only $16 billion.
BCSnob 08/27/20 06:47pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

We are not a shipping company. We ship our own products to as far as China, Australia, etc. through customs, with dry ice or cold packs in insulated packaging. Even Omaha steaks are shipped on dry ice: Omaha Steaks Shipping Go read up on the information on “operation warp speed”; it includes scale up manufacturing and distribution.
BCSnob 08/27/20 05:23pm Around the Campfire
RE: 2019–20 CORONAVIRUS PANDEMIC POSTINGS

Even when a vaccine is available we all may not be home free. For example the Moderna and Pfizer vaccine candidates reportedly require low temperature storage and transportation, -4F for Moderna and -94F for Pfizer: https://www.marketwatch.com/story/moderna-and-pfizers-covid-19-vaccine-candidates-require-ultra-low-temperatures-raising-questions-about-storage-distribution-2020-08-27?mod=home-pageThat problem has been solved for decades. Companies (including mine) regularly ship perishable pharmaceuticals on cold packs or dry ice nationwide and internationally.
BCSnob 08/27/20 04:16pm Around the Campfire
RE: Taking the dogs with

Actually, the dogs will be safer in an accident in a well built dog box in the bed of a truck than loose (being thrown around, or ejected) or even in a harness (exposed to flying debris) in the cab of the truck.Not from a heat standpoint, when this was originally posted are area was experiencing record heat over 100 degrees, big difference in location that you did not consider. I about lost a Collie to stupidity on my part. Big difference in hauling dogs in a hunting box in the fall compared to the hottest part of summer.In my mind were people in Texas I know who transport dogs to events all year long. So many of us seem to forget that humans and dogs/canines have survived for centuries in hot climates long before AC was invented. The keys are shade from the sun, good ventilation (a breeze), low activity, and access to water. If this didn’t work coyotes wouldn’t be able to live in places like Death Valley. The problems to address with dogs in contained spaces (like vehicles or dog boxes) are preventing solar heating (shade from the sun/ good insulation) and good ventilation. Brachycephalic breeds are another matter when it comes to the environments they can tolerate. This is not very scientific but it does raise questions on how dog box construction (single wall vs double wall) can impact interior temperature while sitting out in the sun. Video
BCSnob 08/27/20 03:40pm RV Pet Stop
RE: Coronavirus

Here is a preprint on a serological test for SARS-CoV-2 across multiple animal species. This test can be used to determine if a pet (or any other animal) has had Covid-19. Here's how it works. The receptor binding region of the virus (portion of the spike that binds to cells to start the infection) is coated in a plate (test device). Serum from the possibly affected animal is added to the plate and any antibodies against the SARS-CoV-2 spike protein binds to the material coated on the plate. The excess serum is washed out and a species specific detection antibody is added to the plate. Any antibodies that bind to the SARs-CoV-2 material in the plate AND is the same species as the detection antibody will produce a titer signal. The same titer plate can be used for any species; only the detection reagent needs to be selected for the species being tested. Multi-species ELISA for the detection of antibodies against SARS-CoV-2 in animals I forgot to note that this is of interest to the medical community to enable determining what animal species might become reservoirs for this virus.
BCSnob 08/27/20 11:31am RV Pet Stop
Sort by:    Search within results:
Page of 16  
Prev  |  Next


New posts No new posts
Closed, new posts Closed, no new posts
Moved, new posts Moved, no new posts

Adjust text size:




© 2020 CWI, Inc. © 2020 Good Sam Enterprises, LLC. All Rights Reserved.