I have used TST TPMS products for a number of years on our E450 'C' and am satisfied with their performance. Currently using both flow-through and regular 507 products. Battery life is around 1.5-2 years.
The flow-throughs are on the rear duals placed upon Borg solid metal stems so both TPMS sensors are easily accessible from the outer tire side. The regular TPMS sensors are on the front attached directly to the stems on the wheels and fit within the openings in the wheel simulators.
No air leaks on either type of TPMS, have not added air to the fronts for more than 1 year. Started out with about 62psi and have about 60psi currently.
I change the pressure on the rear regularly depending on the outside temperature where we are. I like to have about 78psi cold and 88 psi hot.
The way I program the sensors is that they have small labels from 1-6 that you place on the sensors to track position. Then take the base unit inside with 1 sensor at a time away from the other sensors (so they don't interfere) and the set-up will allow you to associate the sensor with a wheel position.
I don't put a sensor on the spare tire as I carry a tire compressor at all times so would just use that to inflate the spare if needed.
I carry a couple of spare TST sensors just in case. If there is a battery failure I will just swap sensors on the road. Had one flow-through not flow very well which I replaced out of warranty.
2006 Jayco 28', E450 6.8L V10, Bilstein HDs,
Roadmaster Anti-Sway Bars, Blue Ox TigerTrak